Ryari rizwi nka "zahabu yera", kandi izina ryayo rishingiye ku ngaruka zayo zitagereranywa zo kwera ku ruhande rumwe, n'ingorane n'ubuke bwo kuyikuramo ku rundi ruhande.Igihingwa Glycyrrhiza glabra nisoko ya Glabridin, ariko Glabridin ifite 0.1% -0.3% yibirimo byose, nukuvuga, 1000 kg ya Glycyrrhiza glabra ishobora kubona 100g gusaGlabridin, 1g ya Glabridin ihwanye na 1g ya zahabu yumubiri.
Hikarigandine ni umuntu uhagarariye ibimera, kandi ingaruka zayo zo kwera zavumbuwe n’Ubuyapani
Glycyrrhiza glabra ni igihingwa cyubwoko bwa Glycyrrhiza.Ubushinwa nicyo gihugu gifite umutungo w’ibimera ukize cyane ku isi, kandi hari ubwoko bw’ibiti birenga 500 bikoreshwa mu buvuzi, muri byo bukoreshwa cyane ni ibinyomoro.Dukurikije imibare, igipimo cyo gukoresha ibinyomoro kirenga 79%.
Bitewe namateka maremare yo gusaba, aherekejwe nicyubahiro cyinshi, ingano yubushakashatsi ku gaciro k’ibinyomoro ntabwo yarenze imipaka y’imiterere gusa, ahubwo no gusaba kwaguwe.Nk’uko ubushakashatsi bubyerekana, abaguzi bo muri Aziya, cyane cyane mu Buyapani, bubaha cyane amavuta yo kwisiga arimo ibintu bikomoka ku bimera.Ibintu 114 byo kwisiga byatsi byanditswe muri "Ubuyapani Rusange Cosmetics Raw Materials", kandi hari amoko 200 yo kwisiga arimo ibintu by’ibimera mu Buyapani.
Birazwi ko bifite ingaruka nziza cyane, ariko ni izihe ngorane mubikorwa bifatika?
Igice cya hydrophobique yikuramo ibinyomoro birimo flavonoide zitandukanye.Nkibice byingenzi bigize hydrophobique, halo-glycyrrhizidine igira ingaruka mbi ku musaruro wa melanin kandi ikagira n'ingaruka zo kurwanya inflammatory na anti-okiside.
Amwe mumibare yubushakashatsi yerekana ko ingaruka zera zumucyo Glabridin zikubye inshuro 232 ugereranije na vitamine C isanzwe, inshuro 16 ugereranije na hydroquinone, ninshuro 1,164 ugereranije na arbutine.Kuburyo bwo kugera kumikorere ikomeye yo kwera, urumuri Glabridin rutanga inzira eshatu zitandukanye.
1. Kubuza ibikorwa bya tyrosinase
Uburyo nyamukuru bwo kwera bwaGlabridinni ukubuza synthesis ya melanin mukurwanya guhatanira guhagarika ibikorwa bya tyrosinase, gukuramo igice cya tyrosinase kumpeta ya catalitiki ya melanin synthesis no gukumira guhuza substrate na tyrosinase.
2. Ingaruka ya Antioxydeant
Irashobora guhagarika ibikorwa byombi byo guhinduranya tyrosinase na dopa pigment hamwe nigikorwa cya dihydroxyindole carboxylic aside oxyde.
Byerekanwe ko ku gipimo cya 0.1mg / ml, Photoglycyrrhizidine ishobora gukora kuri sisitemu ya okiside ya cytochrome P450 / NADOH no gukuramo 67% ya radicals yubuntu, ifite ibikorwa bikomeye bya antioxydeant.
3.Buza ibintu bitera umuriro kandi urwanye UV
Kugeza ubu, ubushakashatsi buke bwatangajwe ku ikoreshwa rya Photoglycyrrhizidine mu bushakashatsi bwakozwe ku ifoto y’uruhu iterwa na UV.Mu 2021, mu kiganiro cyo mu kinyamakuru cy’ibanze Ikinyamakuru cya Microbiology na Biotechnology, liposomes ya Photoglycyrrhizidine yakozwe ku bushobozi bwabo bwo gukiza UV iterwa na erythma n’indwara y’uruhu hirindwa ibintu bitera umuriro.Liposomes ya Photoglycyrrhizidine irashobora gukoreshwa mugutezimbere bioavailable hamwe na cytotoxicitike nkeya hamwe no kubuza melanin nziza, kugabanya neza imvugo ya cytokine ikongora, interleukin 6 na interleukin 10. Kubwibyo, irashobora gukoreshwa nkumuti wingenzi wo kuvura imishwarara ya UV iterwa nuruhu. mukubuza gucana, bishobora gutanga ibitekerezo bimwe mubushakashatsi bwibicuruzwa birinda izuba.
Muri make, ingaruka zo kwera za Photoglycyrrhizidine ziramenyekana, ariko imiterere yacyo ntishobora gukemuka mumazi, bityo rero irasaba cyane cyane uburyo bwo gukora no gukora mugukoresha ibicuruzwa byita kuruhu, kandi kuri ubu ni igisubizo cyiza binyuze muri liposome tekinoroji.Byongeye, ifotoGlabridinliposomes irashobora gukumira ifoto ya UV iterwa no gufotora, ariko iyi mikorere ikeneye ubushakashatsi bwamavuriro kugirango bwemeze kandi ubushakashatsi bugashyirwa mubikorwa.
Ibicuruzwa byita kuruhu birimo ifotoGlabridin muburyo bwo guhuza ibintu.
Mugihe ntagushidikanya ko ifotoGlabridine igira ingaruka nziza cyane yo kwera, igiciro cyibikoresho byacyo nabyo birabujijwe kubera ingorane zo gukuramo nibirimo.Mu kwisiga R&D, umurimo wo kugenzura ibiciro uhujwe neza nibirimo tekinoloji hamwe na siyansi.Kubwibyo, nuburyo bwiza bwo kugenzura ibiciro byimikorere no kugera kubwiza bwiza kandi bunoze muguhitamo ibintu bikora no kubihuza muguhuza na Photoglycyrrhizidine.Usibye kurwego rwa R&D, hakenewe ubundi bushakashatsi bujyanye nubushakashatsi bwa liposomes ya Photoglycyrrhizidine hamwe nubuhanga bugezweho bwo kuvoma.
Igihe cyo kohereza: Kanama-30-2022