Chlorphenesin

Chlorphenesin.Ni imiti yagutse ya antiseptique na antibacterial agent, igira ingaruka za antiseptique kuri bacteri za Gram-positif, bacteri za Gram-mbi, imisemburo hamwe na mold.Byemejwe gukoreshwa mu kwisiga n'ibihugu byinshi n'uturere nk'Uburayi, Amerika, Ubuyapani, n'Ubushinwa.Imikoreshereze ntarengwa yemejwe n amategeko n'amabwiriza menshi yigihugu ni 0.3%.
Chlorphenesinntabwo yigeze ikoreshwa muburyo bwo kubungabunga ibidukikije, ahubwo ni nka immunosuppressant ifitanye isano na antigen ibuza irekurwa rya gistamine IgE yunganirwa mu nganda zimiti.Muri make, ni anti-allergique.Nko mu 1967, uruganda rwa farumasi rwize ku ikoreshwa rya chlorphenesin na penisiline kugirango hirindwe ingaruka ziterwa na allergique ziterwa na penisiline.Mu 1997 ni bwo chlorphenesine yavumbuwe n’Abafaransa kubera ingaruka zayo zo kurwanya antiseptique na bacteriostatike hanyuma isaba patenti zijyanye nayo.
1. Chlorphenesin yaba imitsi iruhura?
Raporo y'isuzuma yerekanye neza: ibikoresho byo kwisiga chlorphenesin nta ngaruka zigabanya imitsi.Kandi byavuzwe inshuro nyinshi muri raporo: Nubwo amagambo ahinnye y’icyongereza y’ibikoresho bya farumasi chlorphenesin na cosmetic ingredient chlorphenesin byombi ari Chlorphenesin, byombi ntibigomba kwitiranywa.
2. Ese chlorphenesine irakaza uruhu?
Haba ku bantu cyangwa ku nyamaswa, chlorphenesin ntigira uburakari ku ruhu rusanzwe, nta nubwo ikangura uruhu cyangwa ifotora.Hano hari ingingo enye cyangwa eshanu gusa zerekeye raporo ya chlorphenesine itera uruhu.Hariho ibihe bike aho chlorphenesine yakoreshejwe ni 0.5% kugeza 1%, irenze kure kwibanda kumikoreshereze yo kwisiga.Mu bindi bihe byinshi, byavuzwe gusa ko chlorphenesine yari muri formula, kandi nta kimenyetso cyerekana ko chlorphenesine yateje dermatite.Urebye ikoreshwa ryinshi rya chlorphenesine mu kwisiga, ibi bishoboka rwose ni bike.
3. Ese chlorphenesine izinjira mumaraso?
Ubushakashatsi bw’inyamaswa bwerekanye ko zimwe muri chlorphenesine zinjira mu maraso nyuma yo guhura n’uruhu.Byinshi mu byinjijwe na chlorphenesine bizahinduka mu nkari, kandi byose bizasohoka mu mubiri mu masaha 96.Ariko inzira yose ntabwo izatanga ingaruka mbi zuburozi.
4. Chlorphenescine izagabanya ubudahangarwa?
Ntabwo.Chlorphenesin ni immunosuppressant ya antigen ihindagurika.Mbere na mbere, chlorphenesine igira uruhare runini iyo ihujwe na antigen yagenwe, kandi ntigabanya ubudahangarwa bw'umubiri, cyangwa ngo yongere ubwandu bw'indwara.Icya kabiri, nyuma yo guhagarika ikoreshwa, ingaruka zo gukingira antigen zagenwe zizashira, kandi nta ngaruka zirambye.
5. Ni uwuhe mwanzuro wanyuma wo gusuzuma umutekano?
Ukurikije porogaramu zisanzweho no gukoresha ibitekerezo muri Amerika (gukaraba 0.32%, ubwoko bwabaturage 0,30%), FDA yizera kochlorphenesinni umutekano nkibintu byo kwisiga.