Farumasihodynamics ya chloroxylenol

Chloroxylenol, cyangwa para-chloro-meta-Xylenol (PCMX), ni umukozi uzwi cyane uzwi kandi ahendukira. Numukozi usukura wakoreshwaga muri telefone yibitaro kugirango isukure ibikoresho byo kubaga.

Chloroxylenol nimwe mubikoresho bifatika bikoreshwa mugukora amasabune ya antiseptic. Na none, ibyifuzo byayo bigabanya kunyuramo no murugo nkibintu byangiza.

Dukurikije urutonde rwumuryango wubuzima bwisi bwisi, chloroxylenol hashobora kwangwa na bagiteri zizwi nka gram-nziza, zanditswe neza.

Ariko, urakeneye umukozi mwiza cyane kandi utazima kubarugo kandi ibitaro byawe, ugomba kuvugana nifarangaChloroxylenoluruganda.

Ikimenyetso cya farumasi cya chloroxylenol

Porogaramu ya Chloroxyylenol ivugwa neza mubuvuzi.

Byakoreshejwe mbere mu kuvura indwara zuruhu nko gushushanya, gukata, kurumwa, impeta, nisumu yintoki.

Farumasihodynamics ya chloroxylenol

Chloroxylenolni umusimbura fenol, bivuze ko ifite itsinda rya hydroxyl muburyo bwayo.

Gusaba kwayo bizwi cyane mumyaka nkimwe mubigize bigize ibicuruzwa byica mikorobe. Porogaramu yacyo isabwa hanze ya selire.

Ibikorwa byayo byo kurwanya ku mafaranga make ku itsinda rya bagiteri rivugwa.

Uburyo bwo gukora

Kubaho kw'amatsinda ya hydroxyl muburyo bwayo nibyingenzi cyane, mugihe ubushobozi bwa farumasi bugomba gusobanurwa.

Itsinda rya Hydroxyl rifatwa ku mbuga za poroteyine, na we, mfasha mu kubuza bagiteri zitera.

Chloroxylenol yinjira muri kaliki yo gutera byinshi hamwe nimvugo na poroteyine. Iyo ibi bikozwe, bikuraho ibikorwa bya selire.

Bizagera kurwego rwinshi ya chloroxylenol ikoreshwa kuri selile zikaba ziva mu rupfu rwabo.

Metabolism ya chloroxylenol

Kugirango ibyangombwa bikwiye bya chloroxylenol nkumukozi wa bagiteri kandi utangiza, inyamaswa zakoreshejwe mukwiga byimazeyo ibikorwa byubushobozi bwayo.

Inyamaswa isaba yerekanaga bitewe nigitere cya Chloroxyylenol, igipimo cyo kwibizwa cyari cyihuta cyane mumasaha abiri yambere.

Byagaragaye kandi ko ibintu byahawe amatungo byitwaga binyuze mu mpyiko hamwe no kuvanaho neza ku muvuduko w'amasaha 24.

Ibice byingenzi byagaragaye muri sape yashinzwe harimo glucupronides na sulfate.

Ibyinshi mubintu byubushakashatsi byerekeranye na chloroxylenol byagereranije ibikorwa byayo kuri antibacteried azwi cyane kandi yashushanyije neza antibacterial yitwa Triclosan. Raporo yerekanye ko Glucuronides nayo yari mu cyitegererezo cyakorewe mu cyitegererezo cya muntu.

Ikirenzeho, uhereye ku nyigisho z'umuntu, byafashwe ko buri wese m 5 yajyanywe mu mubiri nyuma yo kwizihiza aside igera kuri 14%.

Ariko, ingano ya chloroxylenol yajyanywe muri sisitemu izaza guswera numwijima kandi yirukanwa nka slucfate na glucuronic.

Inzira yo Kurandura

Nkuko bigaragara hejuru yubushakashatsi byakorewe hamwe na chloroxylenol byerekana ko inzira nyamukuru ya chloroxylenol ikurwa muri sisitemu nyuma yubuyobozi binyuze muri inkari.

Nubwo, ingano nto cyane ifatwa ko ari muri bile kandi nkeya cyane mumuyaga wahawe.

Ukeneye chloroxylenol?

NezaKanda hanoUyu munsiChloroxylenolKubicuruzwa byawe byose antiseptic nibicuruzwa byangiza, kandi tuzishimira cyane gufatana nawe kubicuruzwa byiza.