Cinnamaldehyde ihwanye na 85% ~ 90% by'amavuta ya cinnamoni, naho Ubushinwa ni kamwe mu turere tw’ibihingwa bya cinomu, kandi umutungo wa cinnamaldehyde urakungahaye.Imiterere ya Cinnamaldehyde (C9H8O) ni itsinda rya fenyl rihujwe na acrylein, muburyo busanzwe bwumuhondo cyangwa umuhondo wijimye wijimye wijimye, hamwe na cinnamoni idasanzwe kandi ikomeye hamwe nuburyohe bwa kokiya, irashobora gukoreshwa mubirungo hamwe nibiryo.Kugeza ubu, hari raporo nyinshi zerekeye ibikorwa byinshi bya antibacterial antibacterial ya cinnamaldehyde hamwe nuburyo bukoreshwa, kandi ubushakashatsi bwerekanye ko cinnamaldehyde igira ingaruka nziza za antibacterial kuri bagiteri na fungi.Mu rwego rw'ubuvuzi, ubushakashatsi bumwe na bumwe bwasuzumye aho ubushakashatsi bwakozwe na cinnamaldehyde mu ndwara ziterwa na metabolike, indwara zifata imiyoboro y'amaraso, kurwanya ibibyimba n'ibindi, maze basanga cinnamaldehyde ifite anti-diyabete, kurwanya umubyibuho ukabije, kurwanya ibibyimba n'ibindi ibikorwa bya farumasi.Kubera amasoko akungahaye, ibirungo karemano, umutekano, uburozi buke, uburyohe budasanzwe hamwe ningaruka za antibacterial antibacterial, ni inyongeramusaruro y'ibiribwa yemejwe n’ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge n’Ubushinwa.Nubwo umubare ntarengwa utagabanijwe gukoreshwa, guhindagurika kwayo nimpumuro mbi bigabanya gukoreshwa kwinshi mubiribwa.Gushyira cinnamaldehyde muri firime ipakira ibiryo birashobora kunoza imikorere ya antibacterial kandi bikagabanya ingaruka zibyumva kubiribwa, kandi bikagira uruhare mukuzamura ireme ryububiko bwibiryo no gutwara no kwagura ubuzima.
1. Antibacterial composite membrane matrix
Ubushakashatsi bwinshi bwakozwe kuri firime ya antibacterial ipakira ibiryo ikoresha ibintu bisanzwe kandi byangirika nka matrise ikora firime, kandi firime yo gupakira itegurwa no gutwikira, guterera cyangwa uburyo bwo gukuramo ubushyuhe bwinshi.Bitewe nuburyo butandukanye bwibikorwa no guhuza hagati ya membrane itandukanye hamwe nibintu bikora, imiterere ya membrane yarangiye iratandukanye, nuko rero ni ngombwa cyane guhitamo igikwiye gikwiye.Ubusanzwe bukoreshwa muri firime zirimo ibintu byangiza ibinyabuzima nka alcool ya polyvinyl na polypropilene, ibintu bisanzwe nka polysaccharide na proteyine, hamwe nibintu byinshi.Inzoga ya Polyvinyl (PVA) ni polymer igizwe n'umurongo, ubusanzwe ikora imiterere y'urusobekerane rw'imiterere itatu iyo ihujwe, kandi ifite imiterere ya mashini nziza hamwe na barrière.Ibikoresho bisanzwe bisa na matrix ni byinshi kandi biva cyane.Kurugero, aside polylactique irashobora gusemburwa mubikoresho fatizo nka krahisi n'ibigori, bifite amasoko ahagije kandi ashobora kuvugururwa, biodegradabilite nziza na biocompatibilité, kandi nibikoresho byiza byangiza ibidukikije.Matrix ikomatanya akenshi igizwe na matrices ebyiri cyangwa nyinshi, zishobora kugira uruhare rwuzuzanya ugereranije na matrike imwe.
Ibikoresho bya mashini hamwe nimbogamizi nibintu byingenzi byerekana ibipimo bifatika byo gupakira.Kwiyongera kwa cinnamaldehyde bizahuza na materix ya polymer membrane bityo bigabanye umuvuduko wa molekile, kugabanuka kuramba kuruhuka biterwa no guhagarika imiterere ya neti ya polysaccharide, kandi kwiyongera kwingufu ziterwa no kwiyongera kwitsinda rya hydrophilique mugihe cyo gukora firime yatewe no kongeramo cinnamaldehyde.Byongeye kandi, ubwinshi bwa gaze ya cinnamaldehyde yibumbiye muri rusange yariyongereye muri rusange, ibyo bikaba bishobora guterwa no gukwirakwiza cinnamaldehyde muri polymer kugirango habeho imyenge, imyanda n’imiyoboro, bigabanya ubukana bwa molekile y’amazi, kandi amaherezo biganisha ku kwiyongera. gaze ya gaze ya cinnamaldehyde igizwe na membrane.Imiterere yubukanishi hamwe nubucucike bwibice byinshi bigize ibice birasa, ariko imiterere numutungo wa polymer substrate zitandukanye ziratandukanye, kandi imikoranire itandukanye na cinnamaldehyde izagira ingaruka kumikorere ya firime ipakira, hanyuma igire ingaruka kubikorwa byayo, bityo rero ni ngombwa cyane guhitamo polymer ikwiye hamwe no kwibanda.
Icya kabiri, cinnamaldehyde no gupakira firime uburyo bwo guhuza
Nyamara, cinnamaldehyde irashobora gushonga gake mumazi hamwe no gushonga kwa mg / mL 1.4 gusa.Nubwo tekinoroji yo kuvanga yoroshye kandi yoroshye, ibyiciro bibiri bya cinnamaldehyde yamavuta na elegitoronike ya matrike ya matrike idahindagurika, kandi ubushyuhe bwo hejuru hamwe numuvuduko ukabije mubisanzwe bisabwa muburyo bwo gukora firime bigabanya cyane kwibumbira hamwe kwa cinnamaldehyde muri membrane.Biragoye kugera ku ngaruka nziza ya bacteriostatike.Ikoreshwa rya tekinoroji nuburyo bwo gukoresha ibikoresho byurukuta kugirango bipfunyike cyangwa byamamaza ibintu bifatika bigomba gushyirwamo imbaraga kugirango bitange inkunga cyangwa kurinda imiti.Gukoresha tekinoroji yo gushira mugukosora cinnamaldehyde mubikoresho bipfunyika birashobora gutuma irekurwa buhoro, igahindura igipimo cyo kugumana, kwagura antibacterial gusaza ya firime, kandi igahindura imiterere yubukorikori bwa firime.Kugeza ubu, uburyo busanzwe bwo kubaka ubwikorezi bwo guhuza cinnamaldehyde na firime yo gupakira birashobora kugabanywamo ibyiciro bibiri: kubaka ubwikorezi bwubukorikori nubwubatsi bwubwikorezi busanzwe, harimo gushiramo polymer, gushyiramo nano liposome, gushyiramo cyclodextrin, guhuza ibumba rya nano cyangwa gupakira.Binyuze mu guhuza ibice byo kwiteranya hamwe na electrospinning, umutwara wa cinnamaldehyde urashobora gutwara neza, kandi uburyo bwibikorwa hamwe nurwego rwa cinnamaldehyde birashobora kunozwa.
Gukoresha cinnamon aldehyde ikora ibiryo bipfunyika
Ubwoko butandukanye bwibiryo bufite amazi atandukanye, ibigize intungamubiri nuburyo bwo kubika no gutwara ibintu, kandi imbaraga zo gukura kwa mikorobe yangirika ziratandukanye cyane.Ingaruka zo kubungabunga cinnamaldehyde antibacterial gupakira ibiryo bitandukanye nabyo biratandukanye.
1. Ingaruka zo kubika neza imboga n'imbuto
Ubushinwa bukungahaye ku mutungo kamere, aho usanga umusaruro n’isoko ry’imboga n'imbuto ari byinshi.Nyamara, ubuhehere hamwe nisukari birimo imboga n'imbuto ni byinshi, bikungahaye ku mirire, kandi bikunze kwanduzwa na mikorobe no kwangirika mugihe cyo kubika, gutwara no kugurisha.Kugeza ubu, ikoreshwa rya firime ipakira antibacterial nuburyo bukomeye bwo kuzamura ububiko nogutwara imboga n'imbuto no kongera igihe cyabyo.Cinnamaldehyde-polylactique acide igizwe na pome ya pome irashobora kugabanya gutakaza intungamubiri, bikabuza gukura kwa rhizopus, kandi bikongerera igihe cyo kubika pome kugeza ku minsi 16.Iyo cinnamaldehyde ikora ibiryo bipfunyika ibiryo byashyizwe mubipfunyika bya karoti bishya, imikurire yumusemburo numusemburo yarabujijwe, igipimo cyangirika cyimboga cyaragabanutse, kandi igihe cyo kuramba cyongerewe kugera kuri 12d.
2. Ingaruka nziza yibicuruzwa byinyama Ibiryo byinyama bikungahaye kuri proteyine, ibinure nibindi bintu, bikungahaye ku mirire nuburyohe budasanzwe.Ku bushyuhe bwicyumba, kubyara mikorobe bitera kwangirika kwa poroteyine zinyama, karubone ndetse n amavuta, bikaviramo kwangirika kwinyama, hejuru yumubiri, ibara ryijimye, gutakaza elastique, numunuko udashimishije.Cinnamaldehyde firime ifungura ibiryo ikoreshwa cyane mugupakira ingurube no gupakira amafi, cyane cyane ibuza imikurire ya Staphylococcus aureus, Escherichia coli, aeromonas, umusemburo, bacteri acide lactique nizindi bagiteri, kandi irashobora kongera igihe cyo kubaho cya 8 ~ 14d.
3. Ingaruka nziza yo kubungabunga amata Kugeza ubu, ikoreshwa ry’ibikomoka ku mata mu Bushinwa ryiyongera uko umwaka utashye.Foromaje nigicuruzwa cyamata gisembuye gifite intungamubiri nyinshi na proteyine.Ariko foromaje ifite ubuzima bwigihe gito, kandi igipimo cyimyanda kubushyuhe buke kiracyahangayikishije.Gukoresha cinnamic aldehyde ibiryo bipfunyika birashobora kongera igihe cyiza cya foromaje, bikaryoha uburyohe bwa foromaje, kandi bikarinda kwangirika kwa foromaje.Kubice bya foromaje hamwe nisosi ya foromaje, ubuzima bwigihe cyongerewe iminsi 45 niminsi 26 nyuma yo gukoresha cinnamaldehyde ipakira neza, ifasha kubika umutungo.
4. Ingaruka nziza yo kubika imigati y'ibiribwa hamwe na cake nibicuruzwa bya krahisi, bikozwe mu gutunganya ifu y'ingano, ipamba yoroshye ya pinusi, biryoshye kandi biryoshye.Nyamara, umutsima na keke bifite ubuzima bwigihe gito kandi birashobora kwanduzwa nindwara mugihe cyo kugurisha, bikaviramo kwangirika kwiza no guta ibiryo.Gukoresha cinnamaldehyde yuzuye ibiryo bipfunyika muri cake ya sponge hamwe numugati ukase birashobora kubuza gukura no gukwirakwira kwa penisilium hamwe nudukara twirabura, kandi bikongerera igihe cyo kubaho kugeza 10 ~ 27d.
Cinnamaldehyde ifite ibyiza byamasoko menshi, bacteriostasis nyinshi nuburozi buke.Nkumukozi wa bacteriostasis mugupakira ibiryo bikora neza, gutuza no kurekura buhoro cinnamaldehyde birashobora kunozwa mukubaka no gutezimbere ubwikorezi bwogutanga, bufite akamaro kanini mukuzamura ububiko no gutwara neza ibiryo bishya no kongera ubuzima bwibiryo.Mu myaka yashize, cinnamaldehyde imaze kugera kuri byinshi no gutera imbere mubushakashatsi bwo kubika ibiribwa, ariko ubushakashatsi bujyanye nabyo buracyari mu ntangiriro, kandi haracyari ibibazo byakemuka.Binyuze mu bushakashatsi bugereranya ingaruka zabatwara ibintu bitandukanye kumiterere yubukanishi nimiterere ya barrière ya membrane, ubushakashatsi bwimbitse bwuburyo bwibikorwa bya cinnamaldehyde nuwitwara hamwe nogusohora kinetic mubidukikije bitandukanye, kwiga ingaruka zamategeko agenga iterambere. ya mikorobe mu biryo byangirika ku biribwa, hamwe nuburyo bwo kugenzura ibipakira antibacterial ku gihe no kurekura umuvuduko wa mikorobe.Gutegura no guteza imbere sisitemu yo gupakira ishobora kuzuza ibisabwa bitandukanye byo kubika ibiryo.
Igihe cyo kohereza: Mutarama-03-2024